https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Anti-inflammatory disease-modifying treatment and short-term disability progression in SPMS https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33927 Wed 23 Jan 2019 15:30:44 AEDT ]]> Predictors of disability worsening in clinically isolated syndrome https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28397 Wed 11 Apr 2018 15:14:13 AEST ]]> Predictors of long-term disability accrual in relapse-onset multiple sclerosis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24856 -22). On-therapy relapses carried greater burden than off-therapy relapses. Cumulative treatment exposure was independently associated with lower EDSS at 10 years (coeff=-0.86, p=1.3x10-9). Furthermore, pregnancies were also independently associated with lower EDSS scores over the 10-year observation period (coeff=-0.36, p=0.009).We provide evidence of long-term treatment benefit in a large registry cohort, and provide evidence of long-term protective effects of pregnancy against disability accrual. We demonstrate that high annualized relapse rate, particularly on-treatment relapse, is an indicator of poor prognosis.]]> Sat 24 Mar 2018 07:11:22 AEDT ]]> The effect of oral immunomodulatory therapy on treatment uptake and persistence in multiple sclerosis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23959 Sat 24 Mar 2018 07:10:07 AEDT ]]> Defining secondary progressive multiple sclerosis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25306 Mon 06 Mar 2023 17:55:37 AEDT ]]>